Misoprostol With Intrauterine Device Insertion

Completed · Not applicable · Has a placebo group

Conditions studied: Contraception

In brief

The purpose of this study is to see if using misoprostol (a medication that softens the cervix) before placing an intrauterine device for contraception reduces pain in women who have never delivered a baby.

Key facts

Study ID

NCT00613366

Run by

Oregon Health and Science University

People needed

40

Starts

2007-06-01

Expected to finish

2010-12-01

Last updated by the study team

2013-03-15

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Nulliparous women (defined as those without a history of pregnancy, despite the outcome, beyond 20 weeks gestation)
• Ages 18-45
• Seeking long-term reversible contraception with an intrauterine device (either Mirena or Paraguard) through the OHSU Center for Women's Health and Planned Parenthood of the Columbia Willamette

You may not qualify if…

• Pregnancy occurring less than 6 weeks from time of presentation
• History of prior intrauterine device placement
• History of Mullerian tract anomalies
• History of uterine surgery
• Allergy or intolerance to misoprostol or other prostaglandin
• Pelvic inflammatory disease (current or within the past 3 months)
• Sexually transmitted diseases (current)
• Puerperal or postabortion sepsis (current or within the past 3 months)
• Purulent cervicitis (current)
• Undiagnosed abnormal vaginal bleeding
• Malignancy of the genital tract
• Known uterine anomalies or fibroids distorting the cavity in a way incompatible with intrauterine device insertion
• Allergy to any component of the intrauterine device or Wilson's disease (for copper- containing intrauterine device)

Where it is running

• Planned Parenthood of the Columbia Willamette — Portland, Oregon, United States
• Oregon Health & Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.