Premenstrual Dysphoric Disorder and Antiepileptic Drugs

Completed

Conditions studied: Epilepsy

In brief

This study is being done to determine if there are differences in mood during the menstrual cycle among women with epilepsy who take various different antiepileptic drugs and women without epilepsy.

Key facts

Study ID

NCT00612235

Run by

Beth Israel Deaconess Medical Center

People needed

80

Starts

2008-04-01

Expected to finish

2010-06-01

Last updated by the study team

2018-10-26

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Women with epilepsy, 18-45 years of age. Women will be on one of 4 established (≥ 3 months) AED monotherapies: LTG, CBZ, PHT or LEV and with documented therapeutic range serum AED level during the year prior to enrollment.
• Normal Control women, 18-45 years of age, in good general health by history

You may not qualify if…

• Concomitant use of prescribed or OTC reproductive hormones
• Concomitant use of antidepressant and anxiolytic medications such as SSRIs, bupropion, tricyclics, benzodiazepines

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Newton-Wellesley Hospital — Newton, Massachusetts, United States

Full record on ClinicalTrials.gov

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