Placebo Controlled Study of Atomoxetine in the Treatment of Mild to Moderate Cognitive Difficulties in Menopausal Women
Completed · Not applicable · Has a placebo group
Conditions studied: Menopause, Cognitive Disturbances
In brief
The purpose of this study is to examine the efficacy of atomoxetine (ATX) treatment for the mild to moderate cognitive disturbances frequently experienced by women during the menopause transition. In addition, we seek to determine, using the Brown Attention Deficit Disorder Scale (BADDS), whether and to what degree peri- and early post-menopausal women experience cognitive disturbances which overlap with the impairments of executive function characteristic of adults with attention deficit disorder (ADHD).
Key facts
- Study ID
- NCT00611533
- Run by
- University of Pennsylvania
- People needed
- 16
- Starts
- 2004-05-01
- Expected to finish
- 2008-04-01
- Last updated by the study team
- 2017-04-17
Who can join
Age: 45 and older, up to 60. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Menopausal subjects between the ages of 45 and 60 years;
- Physically healthy with no major medical illnesses;
- No history within the past 5 years of a DSM-IV psychiatric or substance abuse diagnosis by structured diagnostic interview (SCID);
- Subjects will be determined to be either peri or post-menopausal;
- Subjects must be within 5 years of their last menstrual period;
- Subjective report of cognitive disturbances of at least mild to moderate severity;
- All subjects must be of at least average intelligence as determined using the Wechsler Abbreviated Scale of Intelligence (WASI).
You may not qualify if…
- Clinical evidence of dementia and/or signs of dementia on the Mini-Mental Status Exam (MMSE score of <22);
- History of familial dementia;
- Use of any psychotropic medication within the previous 6 months;
- Use of any estrogen replacement therapy within the previous 6 months;
- Current pregnancy;
- Signs of an unstable medical or neurological disorder.
Where it is running
- Yale University School of Medicine — New Haven, Connecticut, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.