A Feasibility Study of Image Guided Noninvasive Single Fraction Stereotactic Radiosurgery for the Treatment of Brain Metastases
Completed
Conditions studied: Metastatic Brain Cancer
In brief
Stereotactic radiosurgery (SRS) is a way to accurately treat brain tumors. SRS involves the use of a special head frame to keep the head from moving during treatment. The head frame makes very accurate treatment possible. The frame must be attached to the skull with special pins. It feels very tight and can hurt. A special immobilization device can be used to keep the head from moving. This device does not need any pins and does not hurt. We would like to see if the new way of holding the head still can be used for SRS. This is the purpose of the study. New X-Ray machines can be used to find if the head has moved in the mask. We hope that we can use these new tools to treat brain tumors just as accurately without using a head frame. It will make treatment more comfortable for the patient. This is why we are asking patients to join the study.
Key facts
- Study ID
- NCT00610285
- Run by
- Memorial Sloan Kettering Cancer Center
- People needed
- 9
- Starts
- 2005-10-01
- Expected to finish
- 2010-07-01
- Last updated by the study team
- 2015-12-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Histologically confirmed malignancy with the presence of intraparenchymal brain metastases.
- A diagnostic contrast enhanced MRI demonstrating the presence of brain metastases performed within two weeks prior to registration.
- Age ≥ 18 years.
- Must be scheduled or planning to be scheduled for SRS treatment.
- Karnofsky performance status ≥60.
- Patient must sign a study-specific informed consent form. If the patient's mental status precludes his/her giving informed consent, written informed consent may be given by the patient's legal representative.
You may not qualify if…
- Unable to provide informed consent
- Major medical illness including poor cardiac or pulmonary status which would result in inability of the patient to lie down for the procedure.
- Inability to obtain histologic proof of malignancy.
- Younger than 18 years of age.
- Serum creatinine > 1.3 mg/dl.
- Karnofsky performance status of ≤50.
- Allergy to either CT or MR contrast dyes.
Where it is running
- Memorial Sloan Kettering Cancer Center — New York, New York, United States
Full record on ClinicalTrials.gov
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