Magnetic Resonance Imaging in Patients With Breast Cancer
Completed
Conditions studied: Breast Cancer
In brief
The goal of this clinical research study is to learn how often magnetic resonance imaging (MRI) of the breast locates additional areas of cancer in the breast of patients with lobular cancer as well as in the breasts of young breast cancer patients (less than age 40 years). Researchers also hope to learn how often the results of the MRI changes the type of surgical treatment that is recommended and understand the costs associated with using MRI in the diagnostic process. Researchers also want to use a different way of looking at the MRI scans to learn if they can more easily learn the difference between a cyst and a tumor.
Key facts
- Study ID
- NCT00610181
- Run by
- M.D. Anderson Cancer Center
- People needed
- 96
- Starts
- 2008-01-01
- Last updated by the study team
- 2015-07-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with pure invasive lobular carcinoma or mixed invasive ductal-lobular carcinoma with the ductal component not greater that 25% OR patients under the age of 40 at diagnosis, irrespective of tumor histology
- For women with invasive lobular carcinoma, if the pathology report from the diagnostic biopsy states that they have "predominantly" lobular histology or lobular cancer with "focal" areas/nests of ductal carcinoma, these cases will automatically be assumed to have at least 75% lobular component.
- Women with multifocal or multicentric breast cancer are eligible if any one of the biopsy confirmed tumors meets the histologic designations outlined in Inclusion criteria #1 and #2 above.
- Must be able to complete the MR examination within 30 days of mammography and ultrasound of the breast.
- Age >18 years
- Surgery planned at MDACC
- Eastern Cooperative Oncology Group (ECOG) status 0-2
- Creatinine and glomerular filtration rate measured or calculated within 2 weeks of MRI date
You may not qualify if…
- Patients receiving neoadjuvant chemotherapy
- Patients with pacemakers
- Patients with severe claustrophobia
- Obese patients exceeding the equipment weight limits and/or the circumference of the MRI portal
- Interval between MRI and conventional locoregional staging studies (mammography/breast US) greater than 30 days.
- Known allergy to gadolinium
- Patients with clips/prostheses/implanted devices that are not MRI compatible
- Compromised renal function, with a measured or calculated glomerular filtration rate of less than 60 ml/min/1.73m\^2.
Where it is running
- University of Texas MD Anderson Cancer Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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