Diagnostic Yield of Vitreous Biopsy in Sarcoid Uveitis
Completed · Not applicable
Conditions studied: Sarcoidosis-associated Ocular Inflammation
In brief
The usefulness of diagnostic vitrectomy in patients with suspected sarcoidosis with posterior segment involvement (in whom a diagnosis cannot be determined by conventional methods) has not been well described. We hypothesized that diagnostic vitrectomy would help establish the diagnosis in these challenging cases. Herein, we evaluated the diagnostic yield of vitreous biopsy in patients with suspected sarcoidosis-associated uveitis that affected the posterior segment.This is a retrospective interventional case series. Cases of intermediate, posterior or panuveitis that could not be characterized by clinical examination, ancillary, and laboratory tests were considered for diagnostic pars plana vitrectomy. Retrospective chart review was conducted on consecutive eyes that underwent diagnostic, or diagnostic and therapeutic vitrectomy by a single surgeon from January 1989 to June 2006.
Key facts
- Study ID
- NCT00609687
- Run by
- Duke University
- People needed
- 150
- Starts
- 2007-01-01
- Expected to finish
- 2008-01-01
- Last updated by the study team
- 2013-04-11
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Cases were included if intraocular vitreous specimens were obtained for diagnostic testing.
You may not qualify if…
- Patients with acute postoperative or traumatic endophthalmitis from this study were excluded.
Where it is running
- Duke University Eye Center — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.