Brain Imaging of Psychotherapy for Depression

Completed · Not applicable

Conditions studied: Major Depressive Disorder

In brief

The goal of the proposed research is to examine the neural correlates of depressive symptom reduction in individuals with major depressive disorder using functional magnetic resonance imaging (fMRI), and to compare results to those obtained from a nondepressed control group.

Key facts

Study ID

NCT00609453

Run by

University of North Carolina, Chapel Hill

People needed

27

Starts

2006-10-01

Expected to finish

2008-01-01

Last updated by the study team

2012-10-08

Who can join

Age: 21 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• For group 1: Diagnosis of current depression and no other current Axis I psychiatric disorder
• For group 1: Hamilton Depression Rating Scale score of 15 or greater

You may not qualify if…

• A history of serious head injury or neurological disease or psychosis
• Current use of psychoactive medications
• Factors that could affect MRI safety including current or planned pregnancy
• For group 2: current Axis I psychiatric disorder, as assessed by structured clinical interview

Where it is running

• Duke-UNC Brain Imaging and Analysis Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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