Lidocaine and Tetracaine Cream to Treat Postherpetic Neuralgia (PHN)

Completed · Phase 2 · Has a placebo group

Conditions studied: Postherpetic Neuralgia

In brief

Pliaglis™ (lidocaine and tetracaine) Cream 7%/7% is a topical local anesthetic cream that forms a pliable peel on the skin when exposed to air. When applied to intact skin, Pliaglis provides local dermal analgesia by the release of lidocaine and tetracaine from the peel into the skin. Pliaglis is currently approved in the United States for use on intact skin in adults to provide topical local analgesia for superficial dermatological procedures such as dermal filler injection, pulsed dye laser therapy, and facial laser resurfacing. This study will evaluate lidocaine and tetracaine cream 7%/7% for the treatment of pain associated with postherpetic neuralgia (PHN).

Key facts

Study ID

NCT00609323

Run by

ZARS Pharma Inc.

People needed

23

Starts

2008-01-01

Expected to finish

2008-09-01

Last updated by the study team

2012-03-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical diagnosis of PHN.
• Painful PHN areas not located on the face, eye, or in the hair.
• At least 3 months post-vesicle crusting.

You may not qualify if…

• Has broken skin at the target treatment site.
• Is currently on certain prescription medications.
• Doesn't meet criteria due to physical exam findings or medical history.
• Female that is pregnant, breastfeeding, or of childbearing potential and not practicing adequate birth control.

Where it is running

• ZARS Pharma Clinical Site — Lexington, Kentucky, United States
• ZARS Pharma Clinical Site. Reference: SCP-403 — High Point, North Carolina, United States
• ZARS Pharma Clinical Site. Reference: SCP-403 — Winston-Salem, North Carolina, United States
• ZARS Pharma Clinical Site — Norman, Oklahoma, United States
• ZARS Pharma Clinical Site — Oklahoma City, Oklahoma, United States
• ZARS Pharma Clinical Site — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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