Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals.

Completed

Conditions studied: Heroin Dependence, Opioid-Related Disorders

In brief

The purpose is to study how certain factors, including money, the amount of drug available and the amount of work effort, affect opiate drug choice.

Key facts

Study ID

NCT00608504

Run by

Wayne State University

People needed

16

Starts

2007-07-01

Expected to finish

2009-04-01

Last updated by the study team

2012-06-05

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Opioid dependent, as determined by structured clinical interview for DSM-IV (SCID) and Addiction Severity Index (ASI)
• Positive urine test for opiates
• Willing to use an adequate form of contraception for the duration of the study.
• Reads and writes English

You may not qualify if…

• Psychiatric illness, as determined by the DSM-IV criteria
• History of or current neurological disease, including structural abnormalities, seizures, infection, peripheral neuropathy, and head traumas
• History of cardiovascular disease, myocardial infarction, chest pain, or edema
• Systolic blood pressure greater than 160mm HG or less than 95 mm HG: PR diastolic blood pressure greater than 95 mm HG.
• Pulmonary disease, including obstructive pulmonary disease, Cor pulmonale, tuberculosis, and asthma
• Systemic disease (e.g. endocrinopathies, liver or kidney failure, myxedema, hypothyroidism, Addison's disease, autoimmune disease)
• Current alcohol or sedative drug dependence
• Pregnant or breast feeding
• Currently receiving treatment for opioid dependence
• Known phobia of injections

Where it is running

• Wayne State University — Detroit, Michigan, United States

Full record on ClinicalTrials.gov

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