Sympathetic Nerve Activity During Hypoglycemia and Exercise

Completed · Not applicable

Conditions studied: Diabetes Mellitus

In brief

The purpose of this study is to determine if either hypoglycemia or exercise cause differential responses in muscle and skin sympathetic nerve activity.

Key facts

Study ID

NCT00608348

Run by

Vanderbilt University

People needed

36

Starts

2002-04-01

Expected to finish

2008-07-01

Last updated by the study team

2015-06-10

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 36 Healthy male and female subjects (18 males and 18 females) aged 18-40 yr
• All potential volunteers will have routine blood test to screen for hepatic, renal, and hematological abnormalities
• Body mass index ≤30kg · m-2
• Normal bedside autonomic function
• Female volunteers of childbearing potential will undergo HCG pregnancy test at screening and again on the study day.

You may not qualify if…

• Pregnant women
• Subjects unable to give voluntary informed consent
• Subjects on anticoagulant drugs or anemic
• Subjects with a recent medical illness
• Subjects with a history of hypertension, heart disease or cerebrovascular disease
• Subjects with known liver or kidney disease
• Subjects with recent weight loss or consuming a low carbohydrate diet

Where it is running

• Vanderbilt University — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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