Breast MRI as a Preoperative Tool for DCIS

Completed · Not applicable

Conditions studied: Breast Cancer, Ductal Carcinoma in Situ

In brief

Breast MRI is a fairly new technology, but it has been well studied. It is now used routinely in many patients with breast cancer. It has been shown to be useful in detecting areas of cancer that cannot be seen using other types of scans or tests. The purpose of this study is to see how often MRI can find other areas of cancer in women with one area of breast cancer, and to determine how having the MRI test affects their treatment. The purpose is also to study any areas of abnormality seen on your MRI with special methods that allow the images of your breast tissue and the microscopic analysis of your breast tissue to be compared very carefully. The study also aims to follow women who enter the study over a 10-year period to determine how often the breast cancer comes back.

Key facts

Study ID

NCT00605982

Run by

Memorial Sloan Kettering Cancer Center

People needed

115

Starts

2006-10-10

Expected to finish

2025-04-02

Last updated by the study team

2025-04-06

Who can join

Age: 21 and older, up to 59. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age less than 60 at time of consent
• Clinical stage is consistent with Stage 0 or Stage I T1mic at presentation
• Core biopsy proven DCIS or DCIS with microinvasion (invasion ≤0.1 cm), prior to enrollment
• Breast surgery to be performed at MSKCC
• Informed consent obtained
• Female

You may not qualify if…

• Age 60 or over at time of consent
• Patients who are pregnant or nursing
• Patients with contraindications to breast conservation
• Excisional biopsy of DCIS or DCIS with microinvasion, prior to enrollment
• Patients with any contraindications to MRI including pacemaker, tissue expander, other metallic surgical implants, weight over 350 lb., previous gadolinium reaction, metal fragments in eye

Where it is running

• Memorial Sloan Kettering Cancer Center — Basking Ridge, New Jersey, United States
• Memorial Sloan Kettering Cancer Center — Commack, New York, United States
• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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