A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.

Completed · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Macular Edema Associated With Diabetes Mellitus

In brief

The purpose of the study is to test whether Macugen injected into the eye improves vision in more patients than the currently existing standard of care laser therapy. The safety of Macugen compared to standard of care laser will also be evaluated.

Key facts

Study ID

NCT00605280

Run by

Pfizer

People needed

317

Starts

2005-09-01

Expected to finish

2011-07-01

Last updated by the study team

2018-11-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• macular edema associated with diabetes
• visual acuity between 20/50 and 20/200

You may not qualify if…

• recent laser therapy in the eye
• recent signs of uncontrolled diabetes
• blood pressure worse than 160/100
• severe cardiac disease

Where it is running

• Pfizer Investigational Site — Tucson, Arizona, United States
• Pfizer Investigational Site — Los Angeles, California, United States
• Pfizer Investigational Site — Oakland, California, United States
• Pfizer Investigational Site — Santa Ana, California, United States
• Pfizer Investigational Site — Denver, Colorado, United States
• Pfizer Investigational Site — Hamden, Connecticut, United States
• Pfizer Investigational Site — Fort Lauderdale, Florida, United States
• Pfizer Investigational Site — Tampa, Florida, United States
• Pfizer Investigational Site — Tampa, Florida, United States
• Pfizer Investigational Site — Augusta, Georgia, United States
• Pfizer Investigational Site — ‘Aiea, Hawaii, United States
• Pfizer Investigational Site — Indianapolis, Indiana, United States
• Pfizer Investigational Site — Wichita, Kansas, United States
• Pfizer Investigational Site — Boston, Massachusetts, United States
• Pfizer Investigational Site — Detroit, Michigan, United States
• Pfizer Investigational Site — Lynbrook, New York, United States
• Pfizer Investigational Site — New York, New York, United States
• Pfizer Investigational Site — Charlotte, North Carolina, United States
• Pfizer Investigational Site — Pittsburgh, Pennsylvania, United States
• Pfizer Investigational Site — West Columbia, South Carolina, United States
• Pfizer Investigational Site — Abilene, Texas, United States
• Pfizer Investigational Site — Fort Worth, Texas, United States
• Pfizer Investigational Site — Houston, Texas, United States
• Pfizer Investigational Site — McAllen, Texas, United States
• Pfizer Investigational Site — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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