Antidepressant Treatment Plus Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Older Adults
Completed · Not applicable · Has a placebo group
Conditions studied: Generalized Anxiety Disorder
In brief
This study will assess whether adding cognitive behavioral therapy to the antidepressant escitalopram is effective in reducing anxiety in older adults with generalized anxiety disorder.
Key facts
- Study ID
- NCT00601965
- Run by
- Veterans Medical Research Foundation
- People needed
- 73
- Starts
- 2007-10-01
- Expected to finish
- 2011-09-01
- Last updated by the study team
- 2016-08-25
Who can join
Age: 60 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Principal (i.e., most severe or pressing problem) or co-principal current diagnosis of generalized anxiety disorder
- Pretreatment score of at least 17 on Hamilton Anxiety Rating Scale
You may not qualify if…
- Principal diagnosis other than GAD
- Clinically judged too psychiatrically unstable to participate in the study
- Cognitive impairment or dementia
- Alcohol or other substance use disorder within 6 months prior to study entry
- Lifetime diagnosis of schizophrenia, schizoaffective disorder, delusional disorder, or bipolar disorder
- Serious, unstable, or terminal medical condition that would compromise study participation or preclude the use of escitalopram, as determined by a review of medical records
- Use of psychotropics that could not be safely tapered and discontinued for at least 2 weeks prior to study entry
- Use of depot neuroleptics within 6 weeks prior to study entry
- Unwillingness to terminate other forms of psychotherapy
- Already received adequate trial of escitalopram or CBT
Where it is running
- UCSD Outpatient Psychiatric Services — San Diego, California, United States
- Washington University — St Louis, Missouri, United States
- University of Pittsburgh — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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