Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease

Completed · Not applicable

Conditions studied: Lung Cancer

In brief

This research study is being done because patients with a history of chest radiation treatment for Hodgkin's disease have been shown to be at increased risk for developing lung cancer a number of years out from treatment. The risk appears to be further increased among patients with a smoking history. Currently, the practice is to recommend annual low-dose chest CT scans in survivors of Hodgkin's disease who have received prior chest radiation treatment and who have at least a moderate smoking history. In this study, the CT scans will be read and interpreted by the study radiologist, and the results recorded in a consistent manner.

Key facts

Study ID

NCT00601146

Run by

Dana-Farber Cancer Institute

People needed

39

Starts

2006-11-01

Expected to finish

2019-12-01

Last updated by the study team

2020-01-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 5 years or longer from initial Hodgkin's disease diagnosis
• Current age 18 or older
• Received mediastinal irradiation and/or alkylating-agent based chemotherapy
• Smoking history of 10-pack years or more, or current smoker
• Pre-approval from the participant's insurance company for the CT study

You may not qualify if…

• Patients with a history of lung cancer
• Currently receiving treatment for another cancer diagnosis
• Known diagnosis of any metastatic cancer
• Pregnant women

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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