Problem-Solving Therapy for People With Major Depression and Chronic Obstructive Pulmonary Disease

Completed · Not applicable

Conditions studied: Pulmonary Disease, Chronic Obstructive, Depression

In brief

This study will evaluate the effectiveness of problem-solving therapy combined with treatment adherence procedures in treating older people with major depression and chronic obstructive pulmonary disease.

Key facts

Study ID

NCT00601055

Run by

Weill Medical College of Cornell University

People needed

101

Starts

2008-02-01

Expected to finish

2015-08-01

Last updated by the study team

2016-07-15

Who can join

Age: 50 and older, up to 95. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets American Thoracic Society criteria for COPD
• Meets DSM-IV criteria for unipolar major depression
• Scores greater than 19 on 24-item Hamilton Depression Rating Scale
• Fluency in English sufficient for comprehending the questionnaires of the study and for understanding the therapists

You may not qualify if…

• Unable to give informed consent
• Experiencing suicidal thoughts
• History of or currently meets DSM-IV criteria for the following Axis I disorders: psychotic depression, psychotic disorder, bipolar disorder, dysthymic disorder, obsessive compulsive disorder, or current substance abuse
• Meets DSM-IV criteria for Axis II diagnosis of antisocial personality (by SCID-P and DSM-IV)
• Scores less than 24 on Mini-Mental State Exam (MMSE) or meets DSM-IV criteria for dementia
• Certain illnesses (e.g., untreated thyroid or adrenal disease, pancreatic cancer, lymphoma)
• Taking drugs known to cause depression (e.g., reserpine, alpha-methyl-dopa, steroids)
• Current involvement in psychotherapy
• Requires nursing home placement after discharge

Where it is running

• The Burke Rehabilitation Hospital — White Plains, New York, United States
• Weill Medical College of Cornell University — White Plains, New York, United States

Full record on ClinicalTrials.gov

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