The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients

Completed · Not applicable

Conditions studied: Nephrolithiasis, Ureteral Calculi

In brief

The purpose of this study is to determine the efficacy of the α-adrenergic antagonist tamsulosin in the treatment of adult emergency department (ED) patients with ureteral colic secondary to lower ureteral calculus. We hypothesize that there will be no difference in outcomes for subjects treated with and without tamsulosin.

Key facts

Study ID

NCT00600405

Run by

MaineHealth

People needed

81

Starts

2006-08-01

Expected to finish

2007-11-01

Last updated by the study team

2008-01-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age or older;
• able to read, write, and speak English;
• able to use the NRS pain scale; and
• computed tomography diagnosed single lower ureteral calculus

You may not qualify if…

• allergy or sensitivity to the study drug (tamsulosin hydrochloride [Flomax]);
• sulfa/sulfonamide allergy;
• inability to provide informed consent;
• lithiasis of the ureteral intramural tract;
• acute or chronic renal failure;
• fever;
• presence of multiple ureteral stones;
• peptic ulcer disease;
• liver failure;
• concomitant treatment with alpha-lytic drugs, calcium antagonists, nitrates, or vardenafil (Levitra);
• pregnancy;
• breastfeeding; or
• a history of urinary surgery or endoscopic treatment.

Where it is running

• Maine Medical Center — Portland, Maine, United States

Full record on ClinicalTrials.gov

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