Dynamic Contrast Enhanced MRI(DCE-MRI)of Bone Tumors
Completed · Not applicable
Conditions studied: Sarcoma, Bone Tumor
In brief
The purpose of this study is to see whether fast imaging with MRI and the usual contrast material used for MRI, predicts which patients will do well with treatment. Some studies suggest that MRIs done right before surgery may be able to tell how much of the cancer was killed by the chemotherapy. This study will see if this is true in patients with osteogenic sarcoma (OS) and Ewing's sarcoma (ES). This study will also see if MRIs done early in treatment can tell if the chemotherapy is working.
Key facts
- Study ID
- NCT00598741
- Run by
- Memorial Sloan Kettering Cancer Center
- People needed
- 61
- Starts
- 2004-07-01
- Expected to finish
- 2014-04-01
- Last updated by the study team
- 2014-04-10
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All patients with histologically proven diagnoses of OS or Ewing Sarcoma undergoing induction chemotherapy are eligible for study.
- Patients/guardians must provide written consent. It is anticipated that many of these patients will be minors and consent will be obtained from their parent/guardian.
- The presence of the evaluable primary tumor is required.
You may not qualify if…
- Inability to cooperate for an MRI.
- Absence of evaluable primary tumor
- Known reaction to Gd-DTPA
- Pre-operative radiation to primary tumor site
- Contraindication to MRI
- Pacemaker
- Aneurysmal clips
- Metal implants in field of view
- Any other conditions that result in patients not being appropriate for MRI. study
- Pregnancy
- Age and mental status wherein he/she is able to cooperate for MRI study
- Unusual histopathologic subvariants (radiation induced, Paget's disease, hereditary RB)
Where it is running
- Memorial Sloan Kettering Cancer Center — New York, New York, United States
Full record on ClinicalTrials.gov
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