Biomarkers of Molecular Risk in Smokers
Completed
Conditions studied: Smoking Cessation
In brief
Doctors at MSKCC are doing this research study to see if smokers are interested in the idea that genes might be markers of cancer risk, and to see if smokers would want to learn this information about their risk if it were available. Different versions of the gene called UGT1A7 are found in different people. Certain versions of this gene can increase the risk of cancer in people. In this study, doctors will determine the different types of UGT1A7 in smokers and find out whether smokers show good interest and understanding. The information from this study will be used in future studies to identify smokers at increased risk for cancer, and to help smokers quit.
Key facts
- Study ID
- NCT00598143
- Run by
- Memorial Sloan Kettering Cancer Center
- People needed
- 45
- Starts
- 2005-02-01
- Expected to finish
- 2015-05-01
- Last updated by the study team
- 2015-05-28
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Arm A
- 18 years or older;
- >5 packyear history of smoking;
- Ability to understand and sign informed consent.
- Arm B
- 18 years or older;
- >10 packyear history of smoking;
- Intention to taper and/or quit smoking within 6 months
- Ability to understand and sign informed consent.
You may not qualify if…
- Arm A
- Diagnosis of any cancer in the preceding twelve months; (excluding non melanoma skin cancer).
- Arm B
- Diagnosis of any cancer in the preceding twelve months; (excluding non melanoma skin cancer).
- Use of any COX-2 inhibitor, steroid, or non-steroidal anti-inflammatory medication (excluding cardioprotective aspirin > 81mg/d) within one week of urine collection
Where it is running
- Memorial Sloan Kettering Cancer Center — New York, New York, United States
Full record on ClinicalTrials.gov
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