Effect of Raised CBF During CEA on Cognition in DM Patients
Stopped early · Not applicable
Conditions studied: Carotid Artery Disease, Carotid Artery Stenosis, Diabetes, Cognitive Dysfunction
In brief
The purpose of this study is to determine if we can reduce the incidence of cognitive dysfunction - difficulty in performing certain pencil-paper, memory, finger dexterity and thinking type of tasks called neuropsychometric tests - in patients with adult onset diabetes mellitus (DM) undergoing surgery on the carotid artery (CEA). We hypothesize that cognitive dysfunction can be decreased in patients with type II DM by augmenting cerebral blood flow with a shunt during carotid endarterectomy compared to patients with Type II DM who are treated with "conventional" management in which a shunt is placed only if the electroencephalogram (EEG) indicates cerebral ischemia.
Key facts
- Study ID
- NCT00597545
- Run by
- Columbia University
- People needed
- 10
- Starts
- 2007-03-01
- Expected to finish
- 2014-06-01
- Last updated by the study team
- 2015-07-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- ability to speak English
- no history of permanent neurological impairment, Axis I psychiatric diagnosis or drug abuse
- scheduled for elective carotid endarterectomy for treatment of carotid artery stenosis
- diagnosed with diabetes mellitus or HbA1c value greater than 10%
You may not qualify if…
- younger than 18 yrs
Where it is running
- Columbia University, Department of Anesthesiology — New York, New York, United States
Full record on ClinicalTrials.gov
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