Evaluation of Cerebral Spinal Fluid and Blood in Patients With Subarachnoid Hemorrhage
Running, not enrolling
Conditions studied: Subarachnoid Hemorrhage
In brief
In this project we are collecting cerebrospinal fluid and blood from patients at Vanderbilt Medical Center who have a subarachnoid hemorrhage which has followed the rupture of a brain aneurysm. We then propose to study the cerebrospinal fluid using a novel microscopic laser directed mass spectrometric analysis (MALDI) available at Vanderbilt. The cerebrospinal fluid and blood will then be analysed for different biological markers, protein expression and gene expression. These markers will then be statistically correlated with clinical data including prediction of vasospasm, time to vasospasm and response to standard therapy.
Key facts
- Study ID
- NCT00593268
- Run by
- Vanderbilt University Medical Center
- People needed
- 150
- Starts
- 2004-06-01
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2026-03-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients eligible to participate in this study are those that have a documented subarachnoid hemorrhage from a ruptured cerebral aneurysm or patients who have excess cerebrospinal fluid after a Lumbar Puncture or surgery for tumor resection.
- 18 years of age or older
You may not qualify if…
- Patients or family who are unable to understand the informed consent process will be excluded.
Where it is running
- Vanderbilt University Medical Center, Department of Neurological Surgery — Nashville, Tennessee, United States
Full record on ClinicalTrials.gov
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