Risk Factors for Adult-Onset Brain Tumors

Stopped early

Conditions studied: Brain Neoplasm, Primary, Brain Neoplasms, Malignant, Brain Neoplasms, Benign

In brief

Study Objective: Brain tumors are poorly understood. The purpose of this research is to examine whether factors in lifestyle play a role in brain tumor development. The study will also investigate the contribution of inherited susceptibility to the risk of brain cancer. By gaining a better understanding of these influences, the investigators hope to learn how to prevent brain tumors in future generations, and to develop more effective strategies for treatment. Study Protocol: This is a case-control investigation. Persons affected with a brain tumor are compared to unaffected persons on previous medical history, diet and other factors. Those enrolled in the study will participate in an interview on general background, diet, medical history and lifestyle, and will provide a sample of DNA, clippings of your toenails, and a tap water sample from your home. All procedures are performed in the clinic or through the mail. 'Cases': Cases eligible for the study are persons with a recent diagnosis of a primary brain tumor (glioma or meningioma), at least 18 years of age. 'Controls': Controls in the study are non-family members of patients, similar in age and of the same gender. Suitable controls include in-laws, friends, neighbors and co-workers.

Key facts

Study ID

NCT00592865

Run by

Vanderbilt University Medical Center

People needed

850

Starts

2003-10-01

Expected to finish

2015-01-01

Last updated by the study team

2021-02-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Case: Incident primary glioma or meningioma of any stage, diagnosed within 4 months.
• Control: non-blood relative, friend, co-worker of same gender as case
• Aged 18 and older; either gender; any race

You may not qualify if…

• None

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• H. Lee Moffitt Cancer Center — Tampa, Florida, United States
• Emory University — Atlanta, Georgia, United States
• Kentuckaina Cancer Institute — Louisville, Kentucky, United States
• Vanderbilt University Medical Center, Department of Neurological Surgery — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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