Inflammation as a Predictor in Cardioversion of Atrial Fibrillation

Completed

Conditions studied: Atrial Fibrillation

In brief

The laboratory test, C-Reactive Protein (CRP), has become well established as a marker of inflammation. Recently a high CRP level (indicating an increase in inflammation) was identified as a risk factor for atrial fibrillation. We are conducting this study with patients such as yourself with atrial fibrillation who are planning to undergo cardioversion to determine what sort of relationship exists between CRP levels and atrial fibrillation. We will then look at success rates of converting atrial fibrillation to normal sinus rhythm, compared to patients' CRP levels.

Key facts

Study ID

NCT00590525

Run by

Creighton University

People needed

45

Starts

2004-10-01

Expected to finish

2009-06-01

Last updated by the study team

2009-12-01

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Atrial fibrillation patients referred for DC cardioversion
• On stable medical therapy

You may not qualify if…

• Known chronic inflammatory states such as infections, rheumatoid arthritis or known vasculitides.
• Patients having undergone recent surgery or who are on steroid therapy for any reason will be excluded.

Where it is running

• Creighton University Medical Center — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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