Nasal Potential Difference (NPD) for the Diagnosis of Cystic Fibrosis
Completed · Not applicable
Conditions studied: Cystic Fibrosis
In brief
The purpose of this research study is to provide a novel method for the diagnosis of Cystic Fibrosis (CF). This protocol is designed to test the ability of the cells to regulate the movement of salt and water in people with features of CF in whom the diagnosis is not entirely clear. We will be studying these cells in the nose, by a technique called nasal transepithelial potential difference (NPD).
Key facts
- Study ID
- NCT00589745
- Run by
- Children's Hospital of Philadelphia
- People needed
- 27
- Starts
- 2003-09-01
- Expected to finish
- 2019-12-18
- Last updated by the study team
- 2020-01-29
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All ethnic groups accepted
- Individuals with borderline or normal sweat chloride, one or no identified CFTR mutations and a clinical history suggestive of CF.
- Children less than 6-8 years of age may be unable to cooperate (hold still) for the procedure, or be frightened by the procedure. Sedation may be necessary for performance of the procedure on a young child
You may not qualify if…
- n/a
Where it is running
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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