Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities

Stopped early

Conditions studied: Glioblastoma Multiforme

In brief

The purpose of this study is to determine whether dynamic contrast enhanced MRI (DCE MRI) and high diffusion weighting MRI may be used to distinguish between favorable and unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be correlated with histopathologic findings and clinical responses to radiation therapy with or without chemotherapy.

Key facts

Study ID

NCT00589095

Run by

Yale University

People needed

5

Starts

2006-11-01

Expected to finish

2011-08-01

Last updated by the study team

2014-07-02

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The presence of a primary brain tumor that cannot be completely resected that requires radiation therapy with or without chemotherapy.

You may not qualify if…

• Patients who do not have a primary brain tumor or who are unable to tolerate the environment of the MRI scanner

Where it is running

• Yale University School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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