A Biologic Validation of Biomarkers of Progressive NEC & Sepsis
Status unconfirmed
Conditions studied: Necrotizing Enterocolitis
In brief
Necrotizing enterocolitis (NEC) is a severe, sometimes life-threatening inflammation of the intestine that occurs most often in premature babies. If it progresses, the wall of the intestine may perforate, spilling bacteria and stool into the abdomen. Parts or all of the intestine may die. Despite 30 years of clinical studies, the cause of NEC remains unknown. In this study, we will be conducting an independent case-control validation study to verify the diagnostic and prognostic biomarker panels, develop validated biomarkers on boisensors in preparation for prospective validation studies, and conduct independent prospective validation of biosensor based biomarker panels on clinical samples.
Key facts
- Study ID
- NCT00588718
- Run by
- R. Lawrence Moss
- People needed
- 740
- Starts
- 2007-04-01
- Expected to finish
- 2019-12-01
- Last updated by the study team
- 2018-03-09
Who can join
Age: 0 and older, up to 1. Sex: any. Healthy volunteers: not accepted.
Where it is running
- R. Lawrence Moss, MD, Nationwide Children's Hospital, The Ohio State University, Karl Sylvester, MD, Stanford University, Stanford, Califorinia — Columbus, Ohio, United States
Full record on ClinicalTrials.gov
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