The Use of Breathing Synchronized CT and PET Scans in Radiation Therapy Treatment Planning
Completed · Phase 1
Conditions studied: Lung Cancer, Non-Hodgkin's Lymphoma
In brief
The purpose of this study is to find out whether a new device can help obtain more accurate CT and PET scans of the lungs and chest tumors and the liver and liver tumors to help in delivering radiation therapy. When we breathe, the amount of air in the lung changes. Lung tumors may also move during breathing. Liver tumors may also move with breathing; as the lungs inflate, the liver can be pushed down. A CT scan (a special type of X-ray) is routinely obtained as part of planning for lung or liver radiation therapy. Since patients breathe during this CT scan and their lung or liver tumors move, these CT scans can sometimes be inaccurate. We are now testing a device to only obtain the CT and an additional PET scan while patients are breathing in or out. This will hopefully allow us to deliver radiation with more accuracy.
Key facts
- Study ID
- NCT00588328
- Run by
- Memorial Sloan Kettering Cancer Center
- People needed
- 35
- Starts
- 2000-03-01
- Expected to finish
- 2010-05-01
- Last updated by the study team
- 2015-12-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years old
- Ability to sign informed consent form indicating investigative nature of this study, in keeping with the policies of the hospital.
- Patients must have thoracic disease visible on a Chest CT scan, or liver disease visible on a abdominal CT scan.
You may not qualify if…
- Pregnant women are ineligible. A pregnancy test will be performed on each fertile premenopausal female prior to entry into the study.
- Patients with thoracic or liver disease that is not visible on CT scan
- Patients who are unable to follow directions either due to language difficulties or hearing impairment.
- Patients who are too ill to hold their breath.
Where it is running
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
Full record on ClinicalTrials.gov
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