Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & Cholangitis

Completed

Conditions studied: Colitis, Ulcerative, Cholangitis, Sclerosing

In brief

This study is being done to: To attempt to increase the detection of precancerous colon tissue in patients with chronic ulcerative colitis and primary sclerosing cholangitis; To determine if an investigational scope that can look at the lining of the colon in different ways will help the doctor identify abnormal tissue in patients with chronic ulcerative colitis and concurrent primary sclerosing cholangitis; and To determine if this investigational scope can accurately detect precancerous or cancerous tissue in patients with chronic ulcerative colitis that are known to have had cancerous or precancerous tissue in the past.

Key facts

Study ID

NCT00587236

Run by

Mayo Clinic

People needed

65

Starts

2006-03-01

Expected to finish

2010-08-01

Last updated by the study team

2016-01-14

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• patients requiring a clinically indicated surveillance colonoscopy
• able to give informed written consent
• history of chronic ulcerative colitis and colonic dysplasia/or cancer or primary sclerosing cholangitis

You may not qualify if…

• patients with known colonic obstruction
• INR ./= 2.5 or thrombocytopenia ,50,000
• patients with clinically important cardiopulmonary disease who are unable to safely undergo prolonged conscious sedation
• pregnancy
• symptomatic coronary artery disease

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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