A Research Pilot Study in Healthy Volunteers to Evaluate Biomarkers for Novel Anticancer Treatments
Stopped early · Not applicable
Conditions studied: Healthy
In brief
The overall goal of this study is to determine the feasibility and the variability of several biomarker assays in normal subjects that are relevant to tumor biology and novel anti-cancer treatments, with the goal of refining these assays for use in future therapeutic studies.
Key facts
- Study ID
- NCT00586417
- Run by
- Duke University
- People needed
- 61
- Starts
- 2007-01-01
- Expected to finish
- 2012-11-01
- Last updated by the study team
- 2013-12-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- LOCAL (Raleigh-Durham, Chapel Hill) candidates only!!!
- Age >18 years.
- Ability to understand and the willingness to sign a written informed consent document.
You may not qualify if…
- Subjects may not have major medical or other conditions that might affect the study assays: major surgery or trauma in the past six months, known current pregnancy, diabetes, history of coagulation abnormalities.
- Subjects may not be receiving any investigational agents.
- Subjects may not be taking medications that are likely to significantly affect wound healing or clotting (eg steroids, anti-coagulants, hormonal contraceptives), aspirin > 325mg/d or other NSAID > once per day, birth control pills or other hormonal contraceptives.
- Uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
- HIV-positive patients and patients on combination antiretroviral therapy are ineligible because of the potential for alterations in normal wound healing responses. In addition, subjects who currently have a malignancy or have had malignant disease in the past 5 years are not eligible.
Where it is running
- Duke University Medical Center — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.