The Study of Barrett's Esophagus: What Are the Factors of Progression

Stopped early

Conditions studied: Barrett's Esophagus, Esophageal Neoplasms

In brief

This trial is a multi-center clinical and endoscopic outcomes project involving a single large database of patients with Barrett's Esophagus (BE). The initial goal of this project is to define the incidence and prevalence of cancer and high-grade dysplasia (HGD) in patients with BE. Thus, our hypothesis is that systematic collection of data on the natural history of BE and risk factors for progression of BE will provide useful information to develop a decision model for risk stratification and risk reduction strategies in BE.

Key facts

Study ID

NCT00586404

Run by

Midwest Biomedical Research

People needed

1250

Starts

2007-11-01

Expected to finish

2017-05-01

Last updated by the study team

2017-05-30

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Sex: Male and female
• Age: 18-80 years
• Confirmed BE.

You may not qualify if…

• Columnar mucosa in the distal esophagus but no intestinal metaplasia on biopsy.
• Patients with BE who have undergone endoscopic ablation therapy or enrolled in chemoprevention trials. Since this is a natural history study, patients enrolled in intervention trials (e.g. those undergoing endoscopic ablation of their BE) will be excluded.

Where it is running

• Southern Arizona VA Medical Center — Tucson, Arizona, United States
• Bethesda Naval Medical Center — Bethesda, Maryland, United States
• Department of Veterans Affairs Medical Center — Kansas City, Missouri, United States
• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.