Community-Based Programs for Improving Physical Function in People With Early Knee Osteoarthritis

Completed · Not applicable

Conditions studied: Osteoarthritis

In brief

Osteoarthritis (OA) is the most common joint-related disease and most prevalent form of arthritis in the United States. Pain relievers and anti-inflammatory medications are the most commonly prescribed treatments for OA. These medications, however, cannot completely alleviate OA symptoms. Additional recommended strategies for managing OA include physical and occupational therapy, exercise, and patient education. This study will compare the effectiveness of a physical training program, a self-management training program, and a program including both physical and self-management training for improving physical function in people with early stage knee OA.

Key facts

Study ID

NCT00586300

Run by

University of Arizona

People needed

294

Starts

2003-06-01

Expected to finish

2009-05-01

Last updated by the study team

2012-06-21

Who can join

Age: 35 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of pain on most days (i.e., 4 or more days in a week) in one or both knees for at least 4 months during the year prior to study entry
• Duration of symptoms (defined as pain on most days for at least 4 months in 1 year) of less than 5 years
• Radiographic evidence of grade II knee OA
• Some level of disability, represented as a score of 3 or higher for at least three of the following WOMAC Index items: descending or ascending stairs; walking; bending; and performing daily activities

You may not qualify if…

• Any uncontrolled medical condition that could prevent safe participation in the study (e.g., uncontrolled heart disease, blood pressure, or respiratory conditions)
• Any neurological condition that could affect coordination
• Inflammatory arthritis (e.g., rheumatoid or psoriatic arthritis)
• Participates in aerobic activity or resistance training for more than 60 minutes per week
• History of knee surgery
• Radiographic grade I, III-IV (Kellgren and Lawrence classification)
• Body mass index of at most 37.5 Kg/m2 (Individuals over this limit will be advised to follow a weight loss program and achieve stable weight for 6 months prior to participation.)
• History of a knee corticosteroid injection in the 3 months prior to study entry
• Plans to move from the local area
• Plans to become pregnant during the study

Where it is running

• University of Arizona — Tucson, Arizona, United States

Full record on ClinicalTrials.gov

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