Vascular Effects of Sertraline in Heart Failure

Stopped early

Conditions studied: Heart Failure, Depression

In brief

To determine the effects of chronic sertraline treatment on brachial artery flow-mediated dilation in patients with chronic heart failure and depression

Key facts

Study ID

NCT00585455

Run by

Yale University

People needed

4

Starts

2006-01-01

Expected to finish

2009-07-01

Last updated by the study team

2009-07-23

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chronic heart failure with LVEF<40%, age >21 years
• Depression requiring medical treatment with sertraline

You may not qualify if…

• Known intolerance of sertraline

Where it is running

• Yale University School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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