Evaluation of Kidney Disease in Liver Transplant Recipients

Withdrawn before enrolling

Conditions studied: Kidney Disease, Liver Transplantation

In brief

A non-invasive urinary test that detects kidney injuries in liver transplant (LT) candidates would be useful for monitoring of kidney damage. Particularly, the ability to predict irreversibility of such renal damage or progressive nature of renal disease in LT candidates would be of importance to determine the need for dual kidney-liver transplantation (KLT) versus LT alone. We will correlate kidney histology with cytokine/chemokine profile expression in the urine as a potentially useful noninvasive diagnostic tool.

Key facts

Study ID

NCT00585429

Run by

University of Wisconsin, Madison

People needed

0

Starts

2006-09-01

Expected to finish

2009-12-01

Last updated by the study team

2016-05-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects on the liver transplant wait list, subjects who have received a liver transplant at least 6 months prior to enrollment, or subjects who have normal liver function and are about to undergo kidney biospy for diagnostic purposes.

You may not qualify if…

• Contraindication to kidney biopsy
• Inability to give informed consent

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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