Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks

Completed · Not applicable · Has a placebo group

Conditions studied: Port Wine Stain

In brief

Port wine stains are red birthmarks that without treatment persist for a lifetime. They are frequently found on the face and can be conspicuous and disfiguring, negatively impacting social interactions for these patients. Treating Port wine stains is difficult. The standard of care is to use laser treatment, but over 80% of patients fail to completely clear despite multiple treatments. The growth of additional blood vessels (angiogenesis) following the Laser treatment is likely an important factor in why these lesions persist despite therapy.

Key facts

Study ID

NCT00585247

Run by

University of California, Irvine

People needed

27

Starts

2006-11-01

Expected to finish

2012-08-01

Last updated by the study team

2022-10-21

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of Port Wine Stain birthmark
• Male and female subjects of any age who are in good health.
• Fitzpatrick skin type I-VI

You may not qualify if…

• Pregnant or lactating
• History of cutaneous photosensitivity
• History of hypersensitivity to imiquimod 5% cream or any of its components
• History of photodermatoses

Where it is running

• Beckman Laser Institute Medical and Surgical Cilnic — Irvine, California, United States

Full record on ClinicalTrials.gov

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