Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection

Completed · Phase 2

Conditions studied: Large Polyps in the Gastrointestinal Tract

In brief

For removal of large flat lesions of the gastro-intestinal tract injection of a solution under the lesion creates a "safety" cushion and protects from damage to the gastrointestinal tract wall. Various solutions are currently used, but some of them are easy to inject but quickly dissipate (normal saline),other solutions are more longer lasting (hydroxypropyl methylcellulose, hyaluronic acid, etc) but are very difficult to inject and can be expensive and not always available. The investigators performed previously animal experiments which demonstrated that blood is easy to inject and creates a protective cushion which lasts longer than other fluids which are currently used for protective cushion creation.

Key facts

Study ID

NCT00583466

Run by

Johns Hopkins University

People needed

18

Starts

2007-05-01

Expected to finish

2008-05-01

Last updated by the study team

2017-09-13

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Polyps equal or larger than 1 cm

You may not qualify if…

• Coagulopathy
• Inability to sign informed consent

Where it is running

• Johns Hopkins Hospital — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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