Sulodexide Treatment in Patients With Dense Deposit Disease
Withdrawn before enrolling · Phase 1
Conditions studied: Dense Deposit Disease
In brief
The purpose of this study is to see if a medicine called Sulodexide will help prevent or slow down the progression of Membranoproliferative Glomerulonephritis type II/Dense Deposit Disease. Sulodexide is not yet FDA approved and has not been studied in children. Study aim/hypotheses: to measure the efficacy of Sulodexide treatment in patients with the above disease/s.
Key facts
- Study ID
- NCT00583427
- Run by
- University of Iowa
- People needed
- 0
- Starts
- 2007-12-01
- Expected to finish
- 2009-12-01
- Last updated by the study team
- 2015-06-11
Who can join
Age: 5 and older, up to 20. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients must be 5 yrs. to 20 yrs. old
- Patients must have Membranoproliferative Glomerulonephritis Type II (MPGN2), also known as Dense Deposit Disease (DDD)
You may not qualify if…
- Patients less than 5 years of age or older than 20 years of age
- Patients who DO NOT have a diagnosis of Membranoproliferative Glomerulonephritis (MPGN 2) also known as Dense Deposit Disease
- Evidence of hepatic dysfunction including total bilirubin >2.0mg/dL (34 micromol/L) or liver enzymes >3 times upper limit of normal.
- A history of any major medical condition (excluding DDD), including but not limited to: gastrointestinal bleeding in the past 3 months; HIV; active Hepatitis B or C (current active disease defined as an abnormal liver biopsy or persistent, elevated transaminases, SGOT, SGPT); and other medical conditions deemed serious by the investigator
- any risk of bleeding, including a history of bleeding diathesis and a platelet count <100,000/mm3
- active cancer
- Participation in any experimental drug study in the 60 days prior to entry into this study; or plan to participate in any experimental drug study during the study period.
- Known allergy or intolerance to any heparin-like compounds
- Inability to give an informed consent or cooperate with the study personnel -
Where it is running
- Richard Smith, MD — Iowa City, Iowa, United States
Full record on ClinicalTrials.gov
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