Clinical Outcomes in Hereditary Cancer

Withdrawn before enrolling

Conditions studied: Breast Cancer, Pancreatic Cancer

In brief

Compare the clinical characteristics and post-surgical outcomes (overall survival)of pancreatic cancer patients of Ashkenazi descent with or without germline founder mutations in BRCA1 or BRCA2 . Compare the clinical characteristics and outcomes (time to progression) of breast cancer patients of Ashkenazi descent with or without germline founder mutations in BRCA1 or BRCA2 receiving paclitaxel chemotherapy for metastatic disease.

Key facts

Study ID

NCT00580021

Run by

Memorial Sloan Kettering Cancer Center

People needed

0

Starts

2006-01-01

Expected to finish

2016-01-01

Last updated by the study team

2016-01-28

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Included in DB0363-03
• Jewish religious preference at registration
• Archival material available for testing
• Adequate post-surgical follow-up
• Jewish religious preference at registration
• Archival material available for testing
• Adequate follow-up to determine time to progression

You may not qualify if…

• Subjects will not be included in the analyses if a DNA sample cannot be obtained.

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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