A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate

Stopped early · Not applicable

Conditions studied: Nephropathy

In brief

The purpose of this study is to compare the efficacy of oral N-acetylcysteine and intravenous sodium bicarbonate for the prevention of Contrast-Induced Nephropathy (CIN) after cardiac catheterization.

Key facts

Study ID

NCT00579995

Run by

University of Nebraska

People needed

41

Starts

2005-05-01

Expected to finish

2010-04-08

Last updated by the study team

2023-09-21

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Acute renal failure
• History of Kidney transplant
• Currently receiving N-acetylcysteine
• _ Contraindication of hypersensitivity to N-acetylcysteine or sodium bicarbonate
• Left ventricular ejection fraction
• Pregnant, lactating females
• Allergy to contrast dye

Where it is running

• Unversity of Nebraska Medical Center — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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