Phase I Biomarker Study of Dietary Grape-derived Low Dose Resveratrol for Colon Cancer Prevention
Withdrawn before enrolling · Phase 1
Conditions studied: Colon Cancer
In brief
This study is designed to investigate the dietary influence of grapes in colon cancer prevention. A natural compound found in the skin of grapes, resveratrol, may protect against cancer by acting as an antioxidant (a chemical compound or substance that helps reduce damages due to oxygen). This compound is known to block colon cancer cell lines from growing in the laboratory. The purpose of this study is to determine the minimum amount of resveratrol-rich fresh red grapes needed to exhibit such signs of prevention.
Key facts
- Study ID
- NCT00578396
- Run by
- University of California, Irvine
- People needed
- 0
- Starts
- 2007-12-01
- Expected to finish
- 2007-12-01
- Last updated by the study team
- 2021-01-25
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 18 years of age or older, male or female
- Participants must sign informed consent for enrollment
- Participants must have values for tests included in CBC, CMPAN and UA within normal range or no greater than 1.5x ULN or less than 0.75x LLN at prestudy to proceed to registration
- Participants must have normal limited flexible sigmoidoscopic examination on Day 15 to proceed to re-registration
- To receive Day 28 limited flexible sigmoidoscopy, participants must have taken >80% of prescribed dose of red grapes (based on food diary review)
You may not qualify if…
- Pregnant or lactating (and/or elevated ßHCG at enrollment)
- Known history of diabetes
Where it is running
- University of California, Irvine Medical Center — Orange, California, United States
Full record on ClinicalTrials.gov
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