Assessment of the Functional Significance of Accessory Pudendal Arteries

Completed · Not applicable

Conditions studied: Prostate Cancer

In brief

For patients with Prostate Cancer advances in medical technology have enabled us to identify "accessory" (additional) pudendal arteries (called APA) while performing a laparoscopic radical prostatectomy (a scope with a video camera is used during the surgery). APAs running near the prostate gland are identified in approximately 1 in 3 to 4 patients. However, large APAs, like the ones looked for in this study, are identified in 15-18% of all patients. These arteries are preserved more than 80% of the time, depending on their size and location.With this study, we plan to evaluate whether APAs supply blood to the penis and male erections, as well as the amount supplied.

Key facts

Study ID

NCT00577876

Run by

Memorial Sloan Kettering Cancer Center

People needed

38

Starts

2006-09-01

Expected to finish

2011-10-01

Last updated by the study team

2011-10-27

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• They have selected a LRP, with or without robotic assistance, by Jonathan Colelman, MD, Bertrand Guillonneau, MD, Vincent Laudone, MD, Raul Parra, MD, or Karim Touijer MD for definitive treatment of their prostate cancer after a full discussion of treatment options.

You may not qualify if…

• Patients undergoing Open Radical Prostatectomy
• Patients with prior history of insulin dependent diabetes mellitus
• Patient who have received prior radiation therapy to the pelvis or prostate
• Patients requiring anticoagulation postoperatively
• Known allergy to Phenylephrine, Alprostadil, Papaverine or Phentolamine
• Patients whose systolic blood pressure is below 90 mmHg at the time of evaluation despite routine measures taken by the anesthesiologist at his best criteria.
• Patients with labile hypertension or history of prior priapism
• Patients with penile scarring or penile prosthesis
• Patients with an International Index of Erectile Function score < 24

Where it is running

• Memorial Sloan-Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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