Mechanisms of Hypoglycemia Associated Autonomic Dysfunction Question 2

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Type 1 Diabetes

In brief

The purpose of this study is to determine the way by which Alprazolam (Xanax) an anti-anxiety drug affects specialized molecules in your brain called GABA (A) receptors that alter your body's ability to defend itself from low blood sugar (hypoglycemia). We hypothesize that prior activation of GABA (A) receptors may result in blunting of counterregulatory responses during subsequent hypoglycemia and exercise.

Key facts

Study ID
NCT00574639
Run by
University of Maryland, Baltimore
People needed
14
Starts
2007-07-01
Expected to finish
2016-06-01
Last updated by the study team
2019-09-12

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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