Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs

Withdrawn before enrolling

Conditions studied: Myocardial Infarction, Cerebrovascular Accident, Death, Sudden, Cardiac

In brief

High blood pressure is one of the most common health problems in the United States. There are many drug treatment options for high blood pressure, but these medications are not always effective. People with treated high blood pressure can still suffer from other serious cardiovascular health problems, including heart attack, sudden death, or stroke. Genetic variations may cause some people to be more susceptible to these cardiovascular outcomes despite treatment. This study will identify new gene regions that may influence the effectiveness of high blood pressure drugs in preventing the above mentioned cardiovascular conditions.

Key facts

Study ID

NCT00573092

Run by

University of Washington

People needed

0

Starts

2007-09-01

Expected to finish

2016-11-01

Last updated by the study team

2016-11-09

Who can join

Age: 30 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Experience of a first heart attack, stroke, or sudden death
• Member of the Group Health Center (GHC) treated for high blood pressure
• Enrolled at least 1 year in one of the three study populations
• Treated for high blood pressure with one of the four major classes of high blood pressure drugs (diuretics, beta-blockers, ACE inhibitors, or calcium antagonists)

Where it is running

• Cardiovascular Health Research Unit — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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