Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.

Completed · Phase 2

Conditions studied: Primary Open-Angle Glaucoma, Ocular Hypertension

In brief

To evaluate the safety and efficacy of PF-04217329.

Key facts

Study ID

NCT00572455

Run by

Pfizer

People needed

318

Starts

2007-12-11

Expected to finish

2009-06-26

Last updated by the study team

2021-04-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of primary open-angle glaucoma (including pigmentary or pseudoexfoliative) or ocular hypertension in 1 or both eyes.
• Qualifying intraocular pressure (IOP) in the same eye at the Eligibility 1 and 2 measurements.

You may not qualify if…

• Closed/barely open anterior chamber angle or a history of acute angle closure in either eye.
• Anticipate the need to initiate or modify medication (systemic or topical) that is known to affect intraocular pressure (IOP) during the study period.

Where it is running

• Sall Research Medical Center — Artesia, California, United States
• Eye Research Foundation — Newport Beach, California, United States
• North Bay Eye Associates, Inc. — Petaluma, California, United States
• Centre For Health Care — Poway, California, United States
• Atlantic Institute of Clinical Research — Daytona Beach, Florida, United States
• Florida Health Care Plans — Daytona Beach, Florida, United States
• Eye Associates of Fort Myers — Fort Myers, Florida, United States
• International Eye Associates, PA — Ormond Beach, Florida, United States
• Coastal Research Associates,LLC — Atlanta, Georgia, United States
• Omni Eye Services of Atlanta — Atlanta, Georgia, United States
• Eye Care Centers Management, Inc. — Morrow, Georgia, United States
• The Eye Group of Southern Indiana — Evansville, Indiana, United States
• Taustine Eye Center — Louisville, Kentucky, United States
• Rochester Ophthalmological Group, PC — Rochester, New York, United States
• Charlotte Eye Ear Nose and Throat Associates, PA — Charlotte, North Carolina, United States
• Cornerstone Eye Care — High Point, North Carolina, United States
• Mark J. Weiss, MD. Inc. — Tulsa, Oklahoma, United States
• Glaucoma Care Center at Century Eye Care — Bristol, Pennsylvania, United States
• Wills Eye Institute — Philadelphia, Pennsylvania, United States
• Bluestein Custom Vision — Charleston, South Carolina, United States
• Total Eye Care, PA — Memphis, Tennessee, United States
• Texan Eye Care, PA — Austin, Texas, United States
• Eye Physicians of Austin — Austin, Texas, United States

Full record on ClinicalTrials.gov

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