Retisert and Cataract Surgery in Patients With Severe Uveitis

Completed · Not applicable

Conditions studied: Intermediate Uveitis, Posterior Uveitis

In brief

To review chart data at the Duke Eye Center and determined whether a 3-year fluocinolone acetonide sustained drug delivery system (FA) safely suppressed postoperative inflammation when combined with phacoemulsification and posterior chamber intraocular lens implantation (phaco/PCIOL) in eyes with severe uveitis.

Key facts

Study ID

NCT00570830

Run by

Duke University

People needed

21

Starts

2006-09-01

Expected to finish

2008-05-01

Last updated by the study team

2014-09-03

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A visually significant cataract
• A history of recurrent noninfectious posterior uveitis or intermediate uveitis with or without iridocyclitis
• incomplete therapeutic response or treatment-limiting side effects to oral, periocular corticosteroid, and/or immunosuppressive agents
• VA of at least light perception; and
• Ability to comprehend informed consent and comply with follow-up examinations

You may not qualify if…

• An allergy to fluocinolone acetonide or any component of the delivery system
• A toxoplasmosis scar was present in the study eye,
• A peripheral retinal detachment (RD) in the area of the planned fluocinolone acetonide implant placement
• Required chronic systemic corticosteroid therapy or systemic immunosuppressive therapy to treat non-ocular disease or if they tested positive for human immunodeficiency virus.
• Also excluded were female patients who were pregnant or lactating or not taking precautions to avoid pregnancy.

Where it is running

• Duke University Medical Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.