Tiotropium Induced Bronchodilation in Lung CT Scored Emphysema

Completed

Conditions studied: COPD, Emphysema

In brief

To evaluate if tiotropium (Spiriva)induced bronchodilation of inspiratory capacity in patients with moderate to severe copd subjected to metronome paced hyperventilation induced dynamic hyperinflation is dependent upon the extent of underlying emphysema as determined by high resolution-thin section CT lung.

Key facts

Study ID

NCT00570544

Run by

Gelb, Arthur F., M.D.

People needed

29

Starts

2004-08-01

Expected to finish

2005-08-01

Last updated by the study team

2008-08-14

Who can join

Age: 40 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• moderate to severe copd

You may not qualify if…

• unable to tolerate tiotropium
• unable to perform metronome paced hyperventilation induced dynamic hyperinflation

Where it is running

• Arthur F Gelb Medical Corporation — Lakewood, California, United States

Full record on ClinicalTrials.gov

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