Docetaxel, Trabectedin, and G-CSF or Pegfilgrastim in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer

Completed · Phase 2

Conditions studied: Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer

In brief

RATIONALE: Drugs used in chemotherapy, such as docetaxel and trabectedin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Colony-stimulating factors, such as G-CSF and pegfilgrastim, may help the immune system recover from the side effects of chemotherapy. Giving combination chemotherapy together with G-CSF or pegfilgrastim may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects and how well giving docetaxel and trabectedin together with G-CSF or pegfilgrastim works in treating patients with recurrent or persistent ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cavity cancer.

Key facts

Study ID

NCT00569673

Run by

Gynecologic Oncology Group

People needed

71

Starts

2008-03-01

Last updated by the study team

2018-07-18

Who can join

Age: 18 and older, up to 120. Sex: female. Healthy volunteers: not accepted.

Where it is running

• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• Jonsson Comprehensive Cancer Center at UCLA — Los Angeles, California, United States
• George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus — New Britain, Connecticut, United States
• Tunnell Cancer Center at Beebe Medical Center — Lewes, Delaware, United States
• CCOP - Christiana Care Health Services — Newark, Delaware, United States
• Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
• Rush University Medical Center — Chicago, Illinois, United States
• Hinsdale Hematology Oncology Associates — Hinsdale, Illinois, United States
• St. Vincent Indianapolis Hospital — Indianapolis, Indiana, United States
• Union Hospital Cancer Program at Union Hospital — Elkton, Maryland, United States
• UMASS Memorial Cancer Center - University Campus — Worcester, Massachusetts, United States
• St. John's Regional Health Center — Springfield, Missouri, United States
• Hulston Cancer Center at Cox Medical Center South — Springfield, Missouri, United States
• Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis — St Louis, Missouri, United States
• Cancer Institute of New Jersey at Cooper - Voorhees — Voorhees Township, New Jersey, United States
• University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
• Alamance Cancer Center at Alamance Regional Medical Center — Burlington, North Carolina, United States
• Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
• Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina, United States
• Case Comprehensive Cancer Center — Cleveland, Ohio, United States
• MetroHealth Cancer Care Center at MetroHealth Medical Center — Cleveland, Ohio, United States
• Cleveland Clinic Cancer Center at Fairview Hospital — Cleveland, Ohio, United States
• Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
• Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center — Columbus, Ohio, United States
• Riverside Methodist Hospital Cancer Care — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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