N-acetylcysteine in Alcohol Dependence

Completed · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Alcoholism

In brief

The present study is designed to find out if N-acetylcysteine works in reducing alcohol drinking and craving.

Key facts

Study ID

NCT00568087

Run by

Minneapolis Veterans Affairs Medical Center

People needed

46

Starts

2007-12-01

Expected to finish

2009-08-01

Last updated by the study team

2020-03-18

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age 18 - 65
• alcohol dependence by DSM-IV
• heavy drinking at least 4 times in the past month
• able to provide informed consent

You may not qualify if…

• current drug abuse or dependence by DSM-IV criteria (except nicotine or cannabis)
• current psychotic disorders, bipolar disorders, or cognitive disorders
• current suicidal or homicidal ideation
• positive illicit drug screen (except cannabis)
• Clinical Institute Withdrawal Assessment for Alcohol, Revised >15
• initiation of individual therapy or counseling in the past 3 months
• changes in doses of psychiatric medications in the past 3 months
• clinically unstable cardiac, hepatic, renal, neurologic, or pulmonary disease
• current use of naltrexone, disulfiram or acamprosate
• pregnant or nursing women, or inadequate birth control methods in women of childbearing potential

Where it is running

• Minneapolis VA Medical Center — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.