A Safety and Effectiveness Study of JNJ-18038683 in Patients With Moderate to Severe Depression

Completed · Phase 2 · Has a placebo group

Conditions studied: Major Depressive Disorder

In brief

The purpose of this study is to evaluate the safety and effectiveness of JNJ-18038683 compared to escitalopram and placebo in patients with moderate to severe depression.

Key facts

Study ID

NCT00566202

Run by

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

People needed

67

Starts

2007-12-01

Expected to finish

2008-12-01

Last updated by the study team

2014-08-06

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with moderate to severe major depressive disorder
• Willing to use acceptable methods of birth control throughout the study and for 3 months after
• In good general health

You may not qualify if…

• No history or current diagnosis of other psychiatric conditions such as bipolar disorder, psychotic disorder, general anxiety disorder, anorexia, obsessive compulsive disorder, post traumatic stress disorder, antisocial personality disorder, mental retardation, pervasive developmental disorder, or cognitive disorder
• No history or presence of drug abuse
• No use of prescription medications or herbal medications other than hormone replacement therapies
• No prior history of heart disease or current significant blood, lung, kidney, liver, heart, breathing, neurologic or thyroid disorders
• No patients who are either pregnant or nursing

Where it is running

• Study site — Little Rock, Arkansas, United States
• Study site — Beverly Hills, California, United States
• Study site — Glendale, California, United States
• Study site — San Diego, California, United States
• Study site — Bradenton, Florida, United States
• Study site — Maitland, Florida, United States
• Study site — Orlando, Florida, United States
• Study site — Atlanta, Georgia, United States
• Study site — Eagle, Idaho, United States
• Study site — Chicago, Illinois, United States
• Study site — Prairie Village, Kansas, United States
• Study site — Topeka, Kansas, United States
• Study site — Baton Rouge, Louisiana, United States
• Study site — Shreveport, Louisiana, United States
• Study site — Nutley, New Jersey, United States
• Study site — Brooklyn, New York, United States
• Study site — Cedarhurst, New York, United States
• Study site — Fresh Meadows, New York, United States
• Study site — Cincinnati, Ohio, United States
• Study site — Oklahoma City, Oklahoma, United States
• Study site — Portland, Oregon, United States
• Study site — Norristown, Pennsylvania, United States
• Study site — Memphis, Tennessee, United States
• Study site — Austin, Texas, United States
• Study site — Irving, Texas, United States

Full record on ClinicalTrials.gov

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