Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal Obesity

Completed

Conditions studied: Obesity, Growth Hormone

In brief

Obesity is one of the leading causes of cardiovascular-related diseases, including diabetes and heart disease. Obesity, and more specifically abdominal obesity, may cause decreased growth hormone (GH) levels. It is believed that GH deficiency may contribute to increased cardiovascular risk by affecting insulin resistance, inflammatory markers, and blood cholesterol levels. This study will determine the occurrence of GH deficiency in abdominal obesity and whether GH deficiency is associated with increased cardiovascular risk beyond traditional risk factors.

Key facts

Study ID
NCT00562796
Run by
Massachusetts General Hospital
People needed
149
Starts
2007-11-01
Expected to finish
2011-05-01
Last updated by the study team
2011-08-23

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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