Dynamic Substrate Mapping (DSM) for Ischemic VT
Stopped early · Phase 1
Conditions studied: Ischemic Ventricular Tachycardia
In brief
This is a prospective, non-randomized study to determine the feasibility of using a new technique called Dynamic Substrate Mapping (DSM) to help guide the treatment of ischemic ventricular tachycardia (IVT). We hypothesize that DSM will lead to simpler, more effective ablation of IVT. Results from this study will be used to determine if further clinical investigation is warranted.
Key facts
- Study ID
- NCT00558857
- Run by
- Abbott Medical Devices
- People needed
- 5
- Starts
- 2007-07-01
- Expected to finish
- 2009-04-01
- Last updated by the study team
- 2019-02-04
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Have an ICD or CRT-D device
- Had at least 3 documented device therapies to treat VT over last 3 months
- Clinical VT is confirmed or suspected to be of ischemic origin
- Scheduled for VT ablation procedure
- LVEF > or = 20%
You may not qualify if…
- Inadequate AAD washout (amiodarone should be maintained at current dose)
- Unstable angina
- Active ischemia
- Cardiac surgery within prior 2 months
- Evidence of infection
- Prosthetic mitral or aortic valve or mitral/aortic valvular heart disease requiring surgical intervention
- History of embolic event
- Myocardial infarction within prior 6 weeks
- Enrolled in another study
- Recurrent sepsis or otherwise not a candidate for catheterization
- Hypercoagulable state or inability to tolerate heparin therapy during procedure
- Has had an atriotomy or ventriculotomy within prior 4 months
- Life expectancy < 6 months
- Class IV NYHA classification
Where it is running
- Northwestern University — Chicago, Illinois, United States
- Hospital at the University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Sentara Norfolk General Hospital — Norfolk, Virginia, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.