A Photodynamic Therapy for Treatment of Actinic Keratoses

Completed · Not applicable

Conditions studied: Actinic Keratoses

In brief

The purpose of this study is to compare the efficacy of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light vs absence of treatment for actinic keratoses.

Key facts

Study ID

NCT00558688

Run by

Northwestern University

People needed

20

Starts

2007-08-01

Expected to finish

2009-08-01

Last updated by the study team

2021-12-06

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age greater than or equal to 18 years
• Have a t least 4 nonhypertrophic AK lesions on the body
• The subjects are in good health
• The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate to the investigator

You may not qualify if…

• Subjects who are pregnant or lactating
• Subjects with a history of cutaneous photosensitivity or porphyria, hypersensitivity to porphyrins, or photodermatosis
• Subjects with use of photosensitizing drugs within 1 week of study start
• Subjects with use of topical medications such as corticosteroids, alpha-hydroxyacids or retinoids 2 weeks before study entry
• Subjects with systemic steroid therapy within 4 weeks before study entry
• Subjects who received previous treatment of target AKs
• Subjects with systemic treatment with chemotherapeutic agents, masoprocol (Actinex), immunotherapy, or retinoids within 2 months of study entry
• Subjects with prior history of hypersensitivity reactions to lidocaine
• Subjects who are unable to understand the protocol or to give informed consent

Where it is running

• Northwestern University Department of Dermatology — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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